Supplementation with selenium-rich bread does not influence platelet aggregation in healthy volunteers

Six healthy subjects were supplemented with 200 micrograms selenium (Se) as Se-rich bread to determine the effect of an increased dietary Se supply on platelet glutathione peroxidase and platelet aggregation. Results show that Se supplementation increases platelet glutathione peroxidase activity but has no effect on platelet aggregation. Therefore, it was assumed that increased dietary selenium intake has no influence on platelet aggregation.