Could CuB be the site of redox linkage in cytochrome c oxidase?

Authors :: Larsen, Randy W.
Pan Lian-Ping
Musser, Siegfried M.
Zhuyin Li
Chan, Sunney I.
Source :: Proceedings of the National Academy of Sciences of the United States. Jan 15, 1992, Vol. 89 Issue 2, p723, 5 p.
Publication Year :: 1992
Abstract: CuB site has a possible potential role in the proton pumping activity of cytochrome c oxidase. A model identical to redox-linked exchange mechanism for CuA site can be applied to CuB center as indicated by qualitative analysis. However, the small distance between CuB and cytochrome a3renders the uncoupling electron transfer pathways as facile. This argument coupled with the CuB location in the membrane contradicts the redox linkage proposal for CuB site.

Subjects :: Oxidation-reduction reaction -- Physiological aspects
Respiration -- Physiological aspects
Cytochrome oxidase -- Research
Biophysics -- Research
Science and technology

ISSN :: 00278424
Volume :: 89
Issue :: 2
Database :: Gale General OneFile
Journal :: Proceedings of the National Academy of Sciences of the United States
Publication Type :: Academic Journal
Accession number :: edsgcl.13315210

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