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A novel and highly regioselective approach to 5-methoxy-6-substituted-3-sulfonyl-delta-enlacatams from 5-methoxy-sulfonyl glutarimide: Synthesis of cis-2-substituted-3-piperidinols
- Source :
- Journal of Organic Chemistry. March 4, 2005, Vol. 70 Issue 5, 1780-1785
- Publication Year :
- 2005
-
Abstract
- A convenient method for the preparation of 5-methoxy-6-substituted-3-sulfonyl-delta-enlactams via regioselective nucleophilic addition to 5-methoxy-3-sulfonyl glutarimide is described. Formal syntheses of L-733,060, CP-99,994, and cassine are reported.
- Subjects :
- Nucleophiles -- Research
Biological sciences
Chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 00223263
- Volume :
- 70
- Issue :
- 5
- Database :
- Gale General OneFile
- Journal :
- Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.132899957