Back to Search Start Over

Leflunomide or methotrexate for juvenile rheumatoid arthritis

Authors :
Silverman, Earl
Spiegel, Lynn
Saurenmann, Rotraud K.
Horneff, Gerd
Szer, Ilona S.
Mouy, Richard
Jung, Lawrence K.
Lahdenne, Pekka
Calvo, Immaculada
Simpson, Karen
Stewart, John A.
Strand, Vibeke
Source :
The New England Journal of Medicine. April 21, 2005, Vol. 352 Issue 16, p1655, 12 p.
Publication Year :
2005

Abstract

The safety and efficacy of leflunomide was compared with that of methotrexate in the treatment of polyarticular juvenile rheumatoid arthritis in a multinational, randomized, controlled trial. It was concluded that in patients with polyarticular juvenile rheumatoid arthritis, methotrexate and leflunomide both resulted in high rates of clinical improvement with a slight greater rate for methotrexate.

Subjects

Subjects :
Methotrexate -- Comparative analysis
Methotrexate -- Complications and side effects
Leflunomide -- Comparative analysis
Leflunomide -- Complications and side effects
Rheumatoid arthritis in children -- Care and treatment

Details

Language :
English
ISSN :
00284793
Volume :
352
Issue :
16
Database :
Gale General OneFile
Journal :
The New England Journal of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.132697937

Tools

Authors Abstract Subjects Details