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Intermittent HIV-1 viremia (blips) and drug resistance in patients receiving HAART

Authors :
Nettles, Richard E.
Parsons, Teresa
Flexner, Charles
Kieffer, Tara L.
Cofrancesco, Joseph, Jr.
Carson, Kathryn
Kwon, Patty
Gallant, Joel E.
Ray, Stuart
Monie, Daphne
Quinn, Thomas C.
Persaud, Deborah
Yefei Han
Jackson, Brooks
Siliciano, Robert F.
Source :
JAMA, The Journal of the American Medical Association. Feb 16, 2005, Vol. 293 Issue 7, p817, 13 p.
Publication Year :
2005

Abstract

A hypothesis to test whether blips represent random biological and statistical variation around mean steady-state HIV-1 RNA levels slightly below 50 copies/mL rather than biologically significant elevations in viremia is presented. It is concluded that most blips appear to represent random biological and statistical variation around mean HIV-1 levels below 50 copies/mL rather than clinically significant elevations in viremia.

Details

Language :
English
ISSN :
00987484
Volume :
293
Issue :
7
Database :
Gale General OneFile
Journal :
JAMA, The Journal of the American Medical Association
Publication Type :
Academic Journal
Accession number :
edsgcl.131026692