Back to Search Start Over

Recombinant glutamic acid decarboxylase (representing the single isoform expressed in human islets) detects IDDM-associated 64,000-Mr autoantibodies

Authors :
Karlsen, Allan E.
Hagopian, William A.
Petersen, Jacob S.
Boel, Esper
Dyrberg, Thomas
Grubin, Catherine E.
Michelsen, Birgitte K.
Madsen, Ole D.
Lernmark, Ake
Source :
Diabetes. October 1992, Vol. 41 Issue 10, p1355, 5 p.
Publication Year :
1992

Abstract

GAD is an autoantigen in IDDM. Molecular cloning and specific antibodies allowed us to demonstrate that only the lower [M.sub.r] GAD64 isoform is expressed in human islets, in contrast to [...]

Details

Language :
English
ISSN :
00121797
Volume :
41
Issue :
10
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.12708718