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Enthalpy-driven apolipoprotein A-I and lipid bilayer interaction indicating protein penetration upon lipid binding

Authors :
Arnulphi, Cristina
Lihua Jin
Tricerri, M. Alejandra
Jonas, Ana
Source :
Biochemistry. Sept 28, 2004, Vol. 43 Issue 38, p12258, 7 p.
Publication Year :
2004

Abstract

The interaction of lipid-free apoA-I with vesicles of 1-palmitoyl-2-oleoylphosphatidylcholine (POPC) containing varying amounts of cholesterol using two different approaches, isothermal titration calorimetry (ITC) and circular dichroism (CD) spectroscopy is investigated. ITC yields thermodynamic parameters of interaction and thus provides critical information about the nature of the interaction.

Details

Language :
English
ISSN :
00062960
Volume :
43
Issue :
38
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.126806214