Whole-genome analysis of Alu repeat elements reveals complex evolutionary history

Authors :: Price, Alkes L.
Eskin, Eleazar
Pevzner, Pavel A.
Source :: Genome Research. Nov, 2004, Vol. 14 Issue 11, 2245-2252
Publication Year :: 2004
Abstract: Alu repeats are used to study the history of substitution patterns in the human genome and polymorphic Alu insertions are used as markers to determine genetic distances between human subpopulations. In genome-wide analysis, investigators have identified and statistically validated 213 Alu subfamilies, built an evolutionary tree of these subfamilies.

Subjects :: Genetic markers -- Research
Human genetics -- Research
Genetic research
Health

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