Allylic alkylation versus Michael induced ring closure: chelated enolates as versatile nucleophiles

Authors :: Pohlman, Matthias
Kazmaier, Uli
Lindner, Thomas
Source :: Journal of Organic Chemistry. Oct 1, 2004, Vol. 69 Issue 20, p6909, 4 p.
Publication Year :: 2004
Abstract: Chelated enolates react with excellent selectivities not only in palladium-catalyzed allylic alkylations but also in Michael additions is demonstrated. Chelated amino acid ester enolates are versatile nucleophiles for both reactions giving high yields and selectivities.

Subjects :: Enolates -- Chemical properties
Nucleophiles -- Chemical properties
Chelates -- Chemical properties
Alkylation -- Analysis
Biological sciences
Chemistry

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