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Relaxation-optimized NMR spectroscopy of methylene groups in proteins and nucleic acids

Authors :
Miclet, Emeric
Williams, David C., Jr.
Clore, Marius G.
Bryce, David L.
Boisbouvier, Jerome
Bax, Ad
Source :
Journal of the American Chemical Society. Sept 1, 2004, Vol. 126 Issue 34, p10560, 11 p.
Publication Year :
2004

Abstract

An approach based on relaxation-optimized spectroscopy and multiplet simplification that improves both the resolution and sensitivity of methylene group NMR studies is presented. The approach is applicable both to small molecules and biological macromolecules.

Details

Language :
English
ISSN :
00027863
Volume :
126
Issue :
34
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.124042808