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Design of a new fluorescent cofactor for DNA mehtyltransferases and sequences-specific labeling of DNA
- Source :
- Journal of the American Chemical Society. March 26, 2003, Vol. 125 Issue 12, 3486-3492
- Publication Year :
- 2003
-
Abstract
- A novel approach for sequence-specific labeling of DNA using a newly designed fluorescent cofactor for the DNA methyltransferase from Thermus aquaticus (M.taql) is presented. The new cofactor is used to sequence-specifically label plasmid DNA in a M-Taql-catalyzed reaction.
- Subjects :
- Nucleotide sequence -- Research
DNA -- Research
Chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 125
- Issue :
- 12
- Database :
- Gale General OneFile
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.124030730