Crystal structure of a genomically encoded fosfomycin resistance protein (FosA) at 1.19 angstrom resolution by MAD phasing off the L-III edge of TI

Authors :: Rife, Chris L.
Pharris, Rachel E.
Newcomer, Marcia E.
Armstrong, Richard N.
Source :: Journal of the American Chemical Society. Sept 18, 2002, Vol. 124 Issue 37, p11001, 3 p.
Publication Year :: 2002
Abstract: The characterization and high resolution structure of a protein that exhibits 60% sequence identity to the plasmid-encoded FosA but is encoded in the genome of the opportunistic pathogen Pseudomonas aeruginosa, is described. The structure is solved exploiting the monovalent cation-binding site for multi-wavelength anomalous diffraction (MAD) phasing with thallium(I).

Subjects :: Proteins -- Research
Pseudomonas aeruginosa -- Research
Fosfomycin -- Research
Chemistry

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