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Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early drosophila embryo

Authors :
Aihara, Hitoshi
Nakagawa, Takeya
Yasui, Kiyoshi
Tsutomu, Ohta
Hirose, Susumu; Dhomae, Naoshi;
Takeshima, Yukio; Muramatsu, Masami
Kaneko, Mayumi
Ito, Takashi
Takio, Koji
Source :
Genes & Development. April 15, 2004, Vol. 18 Issue 8, 877-888
Publication Year :
2004

Abstract

Purification and characterization of nucleosomal histone kinase-1 (NHK-1) is shown. NHK-1-catalyzed phosphorylation of conserved serine/threonine residue in H2A is a new histone code component related to cell cycle progression.

Details

Language :
English
ISSN :
08909369
Volume :
18
Issue :
8
Database :
Gale General OneFile
Journal :
Genes & Development
Publication Type :
Academic Journal
Accession number :
edsgcl.122851349