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Simultaneous DNA binding and bending by EcoRV enduclease observed by real-time fluorescence

Authors :
Hiller, David A.
Fogg, Jonathan M.
Martin, Amy M.
Beechem, Joseph M.
Reich, Norbert O.;
Perona, John J.
Source :
Biochemistry. Dec 16, 2003, Vol. 42 Issue 49, 14375-14385
Publication Year :
2003

Abstract

The combining fluorescence anisotropy with fluorescence resonance energy transfer (FRET) measures, the complete catalytic cycle of EcoRV endonuclease. Binding, bending and cleavage of substrate oligonucleotide were monitored in real time anisotropy.

Details

Language :
English
ISSN :
00062960
Volume :
42
Issue :
49
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.121110759