Multiplex three-dimensional brain gene expression mapping in a mouse model of Parkinson's disease

Authors :: Brown, Vanessa M.
Ossadtchi, Alex
Khan, Arshad H.
Yee, Simon
Lacan, Goran
Smith, Desmond J.
Leahy, Richard M.
Cherry, Simon R.
Melega, William P.
Source :: Genome Research. June, 2002, Vol. 12 Issue 6, 868-884
Publication Year :: 2002
Abstract: Voxelation, a new method to facilitate high-throughput three-dimensional imaging of brain gene expression has been developed. An analysis conducted using this method revealed a common network of coregulated genes sharing the normal and PD brain and allowed identification of putative control regions responsible for these network.

Subjects :: Parkinson's disease -- Research
Chromosome mapping -- Research
Gene expression -- Research
Genetic research
Health

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