Encoding method for OBOC small molecule libraries using a biphasic approach for ladder-synthesis of coding tags

Authors :: Xiaobing Wang
Jinhua Zhang
Aimin Song
Lebrilla, Carlito B.
Lam, Kit S.
Source :: Journal of the American Chemical Society. May 12, 2004, Vol. 126 Issue 18, 5740-5749
Publication Year :: 2004
Abstract: A novel method to construct and encode scaffold-based 'one-bead one-compound' (OBOC) peptidomimetic and small molecule libraries, by combining the ladder synthesis mass decoding concepts with a biphasic approach to encoding, is presented.

Subjects :: Chemical compounds -- Labeling
Chemical compounds -- Research
Encoders -- Usage
Encoders -- Research
Chemistry

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