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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitnib

Authors :
Lynch, Thomas J.
Brannigan, Brian W.
Bell, Daphne W.
Harris, Patricia L.
Sordella, Rafaella
Haserlat, Sara M.
Gurubhagavatula, Sarada
Okimoto, Ross A.
Supko, Jeffrey G.
Haluska, Frank G.
Source :
The New England Journal of Medicine. May 20, 2004, Vol. 350 Issue 21, p2129, 11 p.
Publication Year :
2004

Abstract

A study conducted to search for mutations in the epidermal growth factor receptor (EGFR) gene in primary tumors from patients with non-small-cell lung cancer. Screening for such mutations in lung cancers may identify patients with response to gefitinib, is presented.

Details

Language :
English
ISSN :
00284793
Volume :
350
Issue :
21
Database :
Gale General OneFile
Journal :
The New England Journal of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.118768440