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Association between cholesterol level and mortality in dialysis patients: role of inflammation and malnutrition

Authors :
Liu, Yongmei
Coresh, Josef
Eustace, Joseph A.
Longenecker, J. Craig
Jaar, Bernard
Fink, Nancy E.
Tracy, Russell P.
Powe, Neil R.
Klag, Michael J.
Source :
JAMA, The Journal of the American Medical Association. Jan 28, 2004, Vol. 291 Issue 4, p451, 9 p.
Publication Year :
2004

Abstract

Inflammation and malnutrition may cause cholesterol levels to decrease, according to a study of 823 dialysis patients. This could explain why dialysis patients with low cholesterol levels have an increased risk of death. It is not because high cholesterol levels are beneficial, it is because low cholesterol levels are a marker for inflammation and malnutrition. For this reason, dialysis patients with high cholesterol levels should take cholesterol-lowering drugs.

Details

Language :
English
ISSN :
00987484
Volume :
291
Issue :
4
Database :
Gale General OneFile
Journal :
JAMA, The Journal of the American Medical Association
Publication Type :
Academic Journal
Accession number :
edsgcl.112821080