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Monomers and oligomers of the M(sub)2 muscarinic cholinergic receptor purified from Sf9 cells

Authors :
Park, Paul S.-H.
Wells, James W.
Source :
Biochemistry. Nov 11, 2003, Vol. 42 Issue 44, 12960-12971
Publication Year :
2003

Abstract

Research shows that cholinergic M(sub)2 muscarinic receptors may coexist as active monomers and mostly inactive oligomers in the extracts of Sf9 cells. However, upon binding of an antagonist, the purified receptor fraction displays some active oligomers.

Details

Language :
English
ISSN :
00062960
Volume :
42
Issue :
44
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.111110957