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A novel targeted T-cell modulator, efalizumab, for plaque psoriasis

Authors :
Lebwohl, Mark
Tyring, Stephen K.
Hamilton, Tiffani K.
Toth, Darryl
Glazer, Scott
Tawfik, Naji H.
Walicke, Patricia
Dummer, Wolfgang
Wang, Xiaolin
Garovoy, Marvin R.
Pariser, David
Source :
The New England Journal of Medicine. Nov 20, 2003, Vol. 349 Issue 21, p2004, 10 p.
Publication Year :
2003

Abstract

The drug Raptiva from Genentech may be effective in treating severe psoriasis, according to a study of 597 patients. The drug was given as a subcutaneous injection once a week for up to six months. Between 22% and 28% of the patients had a 75% or greater improvement in symptoms, depending on the dose. Raptiva prevents the activation of T cells that cause psoriasis.

Details

Language :
English
ISSN :
00284793
Volume :
349
Issue :
21
Database :
Gale General OneFile
Journal :
The New England Journal of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.110521577