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Efficacy of gefitinib, and inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial

Authors :
Kris, Mark G.
Natale, Ronald B.
Herbst, Roy S.
Lynch, Thomas J., Jr.
Prager, Diane
Belani, Chandra P.
Schiller, Joan H.
Kelly, Karen
Spiridonidis, Harris
Sandler, Alan
Albain, Kathy S.
Cella, David
Wolf, Michael K.
Averbuch, Steven D.
Ochs, Judith J.
Kay, Andrea C.
Source :
JAMA, The Journal of the American Medical Association. Oct 22, 2003, Vol. 290 Issue 16, p2149, 10 p.
Publication Year :
2003

Abstract

The drug Iressa may improve symptoms and cause some tumor shrinkage in patients with non-small cell lung cancer, according to a study of 216 patients. Between one-third and one-half experienced an improvement in their symptoms, depending on which dose they received. In one-fifth of the patients, the drug caused the tumor to shrink at least 50%.

Details

Language :
English
ISSN :
00987484
Volume :
290
Issue :
16
Database :
Gale General OneFile
Journal :
JAMA, The Journal of the American Medical Association
Publication Type :
Academic Journal
Accession number :
edsgcl.109601086