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Heritable activity: a prion that propagates by covalent autoactivation

Authors :
Roberts, B. Tibor
Wickner, Reed B.
Source :
Genes & Development. Sept 1, 2003, Vol. 17 Issue 17, 2083-2087
Publication Year :
2003

Abstract

Research has been conducted on infectious proteins prions. The authors demonstrate that yeast protease B is a prion, which is infectious and reversibly curable, and which is induced via pro-protease overexpression.

Subjects

Subjects :
Gene expression -- Physiological aspects
Cells -- Genetic aspects
Enzymes -- Genetic aspects
Prions -- Genetic aspects
Genetic research -- Analysis
Biological sciences

Details

Language :
English
ISSN :
08909369
Volume :
17
Issue :
17
Database :
Gale General OneFile
Journal :
Genes & Development
Publication Type :
Academic Journal
Accession number :
edsgcl.108638158

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