A 65-kilobase pathogenicity island is unique to Philadelphia-1 strains of Legionella pneumophila

Authors :: Brassinga, Ann Karen C.
Hiltz, Margot F.
Sisson, Gary R.
Morash, Michael G.
Hill, Nathan
Garduno, Elizabeth
Edelstein, Paul H.
Garduno, Rafael A.
Hoffman, Paul S.
Source :: Journal of Bacteriology. August, 2003, Vol. 185 Issue 15-16, p4630, 8 p.
Publication Year :: 2003
Abstract: Nucleotide sequence analysis of an ~80-kb genomic region revealed an ~65-kb locus that bears hallmarks of a pathogenicity island. This locus includes homologues of a type IV secretion system, mobile genetic elements, and known virulence factors. Comparative studies with other Legionella pneumophila strains and serogroups indicated that this ~65-kb locus is unique to L. pneumophila serogroup 1 Philadelphia-1 strains.

Subjects :: Secretion -- Genetic aspects
Legionella pneumophila -- Genetic aspects
Nucleotides -- Genetic aspects
Bacteriology -- Research
Biological sciences

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