Cell fate decisions within the mouse organizer are governed by graded Nodal signals

Authors :: Vincent, Stephane D.
Dunn, N. Ray
Hayashi, Shigemi
Norris, Dominic P.
Robertson, Elizabeth J.
Source :: Genes & Development. July 1, 2003, Vol. 17 Issue 13, 1646-1662
Publication Year :: 2003
Abstract: Research has been conducted on cell fate decisions. Results demonstrate that these decisions are governed by graded Noda1/Smad2 signals, and that Smad2-dependent signals regulate the formation of PCP precursor populations and the definitive endoderm.

Subjects :: Proteins -- Genetic aspects
Central nervous system -- Physiological aspects
Cells -- Genetic aspects
Genetic research -- Analysis
Biological sciences

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