The closely related estrogen-regulated trefoil proteins TFF1 and TFF3 have markedly different hydrodynamic properties, overall charge, and distribution of surface charge

Authors :: May, Felicity E. B.
Church, Stephen T.
Major, Sarah
Westley, Bruce R.
Source :: Biochemistry. July 15, 2003, Vol. 42 Issue 27, 8250-8259
Publication Year :: 2003
Abstract: Research has been conducted on human trefoil proteins TFF1 and TFF3 which are expressed in gastrointestinal tract and expressed and regulated by estrogens in malignant breast epithelial cells. The authors have investigated the charge and hydrodynamic properties of these proteins, and they report that these properties differ significantly.

Subjects :: Hydrodynamics
Estrogen -- Genetic aspects
Estrogen -- Physiological aspects
Epithelium -- Genetic aspects
Epithelium -- Physiological aspects
Genetic regulation -- Analysis
Gene expression -- Physiological aspects
Proteins -- Physiological aspects
Proteins -- Genetic aspects
Biochemistry -- Research
Biological sciences
Chemistry

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