Effect of cilomilast (Ariflo) on TNF-α, IL-8, and GM-CSF release by airway cells of patients with COPD. (Chronic Obstructive Pulmonary Disease)

Authors :: Profita, M.
Chiappara, G.
Mirabella, F.
Giorgi, R. Di
Chimenti, L.
Costanzo, G.
Riccobono, L.
Bellia, V.
Bousquet, J.
Vignola, A.M.
Source :: Thorax. July, 2003, Vol. 58 Issue 7, p573, 7 p.
Publication Year :: 2003
Abstract: Background: Inflammation in chronic obstructive pulmonary disease (COPD) is characterised by increased neutrophilic infiltration of the airways. Cilomilast, a navel selective phosphodiesterase 4 inhibitor in clinical development for COPD treatment, [...]

Subjects :: Phosphodiesterases -- Physiological aspects
Lung diseases, Obstructive -- Drug therapy
Enzyme inhibitors -- Dosage and administration -- Evaluation -- Product/service Evaluations
Health
Ariflo (Medication) -- Evaluation

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