High-resolution SPECT using multipinhole collimation

The authors present a novel SPECT imaging technique for small animal research based on multipinhole collimation. This new method is an extension of single-pinhole tomography and combines high resolution with increased system sensitivity. This paper describes the multipinhole imaging system and its preliminary characterization on simulated and measured phantom data. Index Terms--High resolution, multipinhole, pinhole tomography, small animal imaging, SPECT.