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Design and synthesis of novel fluoropeptidomimetics as potential mimics of the transition state during peptide hydrolysis

Authors :
Annedi, Subhash C.
Li, Weiyong
Samson, Sheeba
Korta, Lakshmi P.
Source :
Journal of Organic Chemistry. Feb 7, 2003, Vol. 68 Issue 3, 1043-1049
Publication Year :
2003

Abstract

Research has been conducted on alpha-fluoroamino acids. The authors report that these acids have been used for the design of fluoropeptidomimetics as potential protease inhibitors.

Details

Language :
English
ISSN :
00223263
Volume :
68
Issue :
3
Database :
Gale General OneFile
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.101566762