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Covalent heme binding to CYP4B1 via Glu310 and a carbocation porphyrin intermediate
- Source :
- Biochemistry. April 22, 2003, Vol. 42 Issue 15, 4601-4606
- Publication Year :
- 2003
-
Abstract
- Research has been conducted on CYP4B1. The authors report their investigation of the heme ester link site in CYP4B1, and their study of the functional consequences of the active site mutations.
- Subjects :
- Biochemistry -- Research
Blood proteins -- Physiological aspects
Carrier proteins -- Genetic aspects
Carrier proteins -- Physiological aspects
Cations -- Genetic aspects
Carbon compounds -- Physiological aspects
Porphyrins -- Physiological aspects
Gene mutations -- Physiological aspects
Biological sciences
Chemistry
Subjects
Details
- ISSN :
- 00062960
- Volume :
- 42
- Issue :
- 15
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.101170745