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Clinical inflammatory biomarkers associated with the tumor stage of gastric cancer: retrospective analysis of a Hospital in Peru during the years 2018–2020 [version 1; peer review: 1 not approved]

Authors :
Jose M. Vela-Ruiz
Katherine Medina-Rojas
Andrea Machón-Cosme
Carlos Perez-Ramos
Miguel J. Sotelo
Jhony A. De La Cruz-Vargas
Author Affiliations :
<relatesTo>1</relatesTo>INSTITUTO DE INVESTIGACIONES EN CIENCIAS BIOMEDICAS, UNIVERSIDAD RICARDO PALMA, LIMA, Peru
Source :
F1000Research. 11:49
Publication Year :
2022
Publisher :
London, UK: F1000 Research Limited, 2022.

Abstract

Introduction: Gastric cancer is a disease with a high rate of morbidity and mortality in the world. Objective: To determine which clinical inflammatory biomarkers are associated with the tumor stage of gastric cancer of the oncology service of the Hospital María Auxiliadora in Lima, Peru, during the years 2018-2020. Methodology: Observational, analytical, cross-sectional and retrospective study. There was a sample of 110 patients. The PR values were obtained from the absolute frequencies of the variables: serum albumin, Platelet-Lymphocyte Ratio (PLR) and Neutrophil-Lymphocyte Ratio (NLR). Results: The average age was 63,727±13.85. 55.45% were female. The most frequent histopathological type was intestinal adenocarcinoma with 62.73%. In the bivariate analysis, an association was found between INL (PR:6.88 CI95% 2.36-20 p Conclusion: INL is an independent predictive factor in relation to the clinical stage of gastric cancer in this study.

Details

ISSN :
20461402
Volume :
11
Database :
F1000Research
Journal :
F1000Research
Notes :
[version 1; peer review: 1 not approved]
Publication Type :
Academic Journal
Accession number :
edsfor.10.12688.f1000research.75119.1
Document Type :
research-article
Full Text :
https://doi.org/10.12688/f1000research.75119.1