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Necrotizing enterocolitis: controversies and challenges [version 1; referees: 3 approved]

Authors :
Augusto Zani
Agostino Pierro
Author Affiliations :
<relatesTo>1</relatesTo>Division of General and Thoracic Surgery, University of Toronto, The Hospital for Sick Children, Toronto, Canada
Source :
F1000Research. 4:F1000 Faculty Rev-1373
Publication Year :
2015
Publisher :
London, UK: F1000 Research Limited, 2015.

Abstract

Necrotizing enterocolitis is a devastating intestinal disease that affects ~5% of preterm neonates. Despite advancements in neonatal care, mortality remains high (30–50%) and controversy still persists with regards to the most appropriate management of neonates with necrotizing enterocolitis. Herein, we review some controversial aspects regarding the epidemiology, imaging, medical and surgical management of necrotizing enterocolitis and we describe new emerging strategies for prevention and treatment.

Details

ISSN :
20461402
Volume :
4
Database :
F1000Research
Journal :
F1000Research
Notes :
Editorial Note on the Review Process F1000 Faculty Reviews are commissioned from members of the prestigious F1000 Faculty and are edited as a service to readers. In order to make these reviews as comprehensive and accessible as possible, the referees provide input before publication and only the final, revised version is published. The referees who approved the final version are listed with their names and affiliations but without their reports on earlier versions (any comments will already have been addressed in the published version). The referees who approved this article are: Paul Tam, Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong No competing interests were disclosed. Patrick Chung, Division of Paediatric Surgery, Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong No competing interests were disclosed. Atsuyuki Yamataka, Department of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan No competing interests were disclosed. David Wesson, Department of Surgery, Texas Children’s Hospital, Houston, TX, USA No competing interests were disclosed., , [version 1; referees: 3 approved]
Publication Type :
Academic Journal
Accession number :
edsfor.10.12688.f1000research.6888.1
Document Type :
review
Full Text :
https://doi.org/10.12688/f1000research.6888.1