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Sea grapes powder with addition of tempe rich in collagen: An anti-aging functional food [version 1; peer review: 1 approved with reservations]

Authors :
Happy Kurnia Permatasari
Fahrul Nurkolis
Christopherous Diva Vivo
Sutamara Lasurdi Noor
Rahmawati Rahmawati
Son Radu
Hardinsyah Hardinsyah
Nurpudji Astuti Taslim
Nelly Mayulu
Defny Silvia Wewengkang
Mury Kuswari
Siti Chairiyah Batubara
William Ben Gunawan
Maizer Said Nahdi
Author Affiliations :
<relatesTo>1</relatesTo>Department of Biochemistry and Biomolecular, Faculty of Medicine, Brawijaya University, Malang, 65145, Indonesia<br /><relatesTo>2</relatesTo>Department of Biological Sciences, Faculty of Sciences and Technology, State Islamic University of Sunan Kalijaga, Yogyakarta, 55281, Indonesia<br /><relatesTo>3</relatesTo>Dentistry, University of Indonesia, Depok, 16424, Indonesia<br /><relatesTo>4</relatesTo>Clinical and Public Health Nutrition Programme, University College London, London, WC1E 6BT, UK<br /><relatesTo>5</relatesTo>Food Technology Department, Sahid University of Jakarta, South Jakarta, 12870, Indonesia<br /><relatesTo>6</relatesTo>Food Sciences, Faculty of Human Ecology, Universiti Putra Malaysia, Serdang Selangor Darul Ehsan, 43400, Malaysia<br /><relatesTo>7</relatesTo>Applied Nutrition, Faculty of Human Ecology, IPB University, Bogor, 16680, Indonesia<br /><relatesTo>8</relatesTo>Clinical Nutrition, Faculty of Medicine, Hasanuddin University, Makassar, 90245, Indonesia<br /><relatesTo>9</relatesTo>Nutrition and Food, Faculty of Medicine, Sam Ratulangi University, Manado, 95115, Indonesia<br /><relatesTo>10</relatesTo>Pharmacy department, Faculty of Mathematics and Sciences, Sam Ratulangi University, Manado, 95115, Indonesia<br /><relatesTo>11</relatesTo>Nutrition Department, Faculty of health sciences, Universitas Esa Unggul, Jakarta, 11510, Indonesia<br /><relatesTo>12</relatesTo>Nutrition Sciences Department, Faculty of Medicine, Diponegoro University, Semarang, 50275, Indonesia
Source :
F1000Research. 10:789
Publication Year :
2021
Publisher :
London, UK: F1000 Research Limited, 2021.

Abstract

Background: This study aimed to determine the potential anti-aging effects of sea grapes and tempe (Fermented soybeans) collagen particle size, by measuring the activities of anti-glycation, antioxidant and tyrosinase inhibitors. Methods: Collagen was isolated from sea grapes and tempe freeze dried powder and treated with different NaOH concentrations (0.10 M; 0.20 M; 0.30 M), and CH 3COOH 1 M solution, separately. The collagen particle size was adjusted by stirring at 1000 rpm for 5 and 10 hours. 2,2-diphenyl-1-picrylhydrazyl (DPPH) was used to measure the antioxidant activity, and L-tyrosine and L-DOPA (l-3,4-dihydroxyphenylalanine) were used as a marker of tyrosine inhibition. Results: The collagen treated with 0.10 M NaOH produced the highest collagen yield (11.65%), and largest particle size (2455 nm). Additionally, this collagen, when treated for 5 hours, exhibited 24.70% antioxidant activity, 62.60% anti-glycation, 8.97% L-tyrosine, and 26.77% L-Dopa inhibition activities. Meanwhile, the collagen treated for 10 hours had a 9.98% antioxidant activity, 41.48% anti-glycation, 7.89% L-tyrosine, and 2.67% L-Dopa inhibition activity. Conclusion: Sea grapes and tempe collagen powder treated with 0.10 M NaOH and stirred for 5 hours, as functional foods have anti-aging properties.

Details

ISSN :
20461402
Volume :
10
Database :
F1000Research
Journal :
F1000Research
Notes :
[version 1; peer review: 1 approved with reservations]
Publication Type :
Academic Journal
Accession number :
edsfor.10.12688.f1000research.55307.1
Document Type :
research-article
Full Text :
https://doi.org/10.12688/f1000research.55307.1