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The antimicrobial effect of Limosilactobacillus reuteri as probiotic on oral bacteria: A scoping review [version 2; peer review: 3 approved]
- Source :
- F1000Research. 12:1495
- Publication Year :
- 2024
- Publisher :
- London, UK: F1000 Research Limited, 2024.
-
Abstract
- Dysbiosis among oral microbial community in the oral cavity can lead to several oral diseases. Probiotic therapy is known to correct these imbalances. Limosilactobacillus reuteri is one of the most studied strains of probiotics and can control oral microbiota through reuterin, a wide-spectrum antimicrobial agent. The objective of this review was to evaluate the effect of the antimicrobial activity of Limosilactobacillus reuteri on the oral bacteria of humans. This review used PubMed, Scopus, EMBASE, ScienceDirect, and Google Scholar databases as bibliographic resources. Studies with matching keywords were analyzed and screened with PRISMA-ScR recommendations. Sixteen articles were selected for this review, which included a total of 832 patients. Based on this review, Limosilactobacillus reuteri has a strong antibacterial effect against Streptococcus mutans in healthy individuals but is not effective against Lactobacillus. Additionally, it has a significant antibacterial effect against Porphiromonas gingivalis in patients with periodontitis, although its effectiveness is not stable in patients with peri-implant infections. Furthermore, Limosilactobacillus reuterihas varying results against other bacteria, indicating the need for further extensive research to ensure its efficacy.
Details
- ISSN :
- 20461402
- Volume :
- 12
- Database :
- F1000Research
- Journal :
- F1000Research
- Notes :
- Revised Amendments from Version 1 Authors are pleased to present the revised version of our manuscript, which incorporates several notable enhancements based on feedback and further research. Here are the key changes made: 1. A brief explanation regarding the utilization of L. reuteri in promoting general health has been included in the discussion section. This addition provides a broader context for understanding the potential applications of L. reuteri beyond the primary focus of the study. 2. We have introduced a paragraph discussing the relationship between L. reuteri and diabetes mellitus. This addition expands the scope of the manuscript and explores an important aspect of the topic. 3. To improve the organization and clarity of the discussion section, we have subdivided it into smaller subheadings. This structural adjustment aims to facilitate easier navigation and comprehension of the presented results. 4. Additional discussion has been incorporated regarding the mechanism of quorum quenching in probiotics, specifically its impact on pathogenic bacteria. Furthermore, we have provided further insights into the cytotoxic effects of Limosilactobacillus reuteri on human gingival fibroblasts. 5. Minor issues related to wording and writing have been addressed to ensure the clarity and coherence of the manuscript. These changes collectively aim to enrich the content and readability of the manuscript, providing readers with a more comprehensive understanding of the topic., , [version 2; peer review: 3 approved]
- Publication Type :
- Academic Journal
- Accession number :
- edsfor.10.12688.f1000research.139697.2
- Document Type :
- systematic-review
- Full Text :
- https://doi.org/10.12688/f1000research.139697.2