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Spectrum of Pituitary disorders: A retrospective study from Basrah, Iraq [version 2; referees: 2 approved]
- Source :
- F1000Research. 7:430
- Publication Year :
- 2018
- Publisher :
- London, UK: F1000 Research Limited, 2018.
-
Abstract
- Background: Pituitary disorders spectrum includes a wide variety of diseases.This study aimed at a comprehensive description of such disorders for patients from Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC) in Basrah (Southern Iraq). Methods: Retrospective data analysis of FDEMC for the period from January 2012 through June 2017. We included all patients with pituitary disorders who have MRI pituitary. Results: The pituitary disorders were more common among women. Those with macroadenoma were older than those with microadenoma with nearly equal gender prevalence of macroadenoma. Pituitary adenoma constituted the bulk of pituitary disorders in this registry (67.2%). Growth hormone secreting adenoma were the commonest adenoma seen in 41.0% followed by clinically non-functioning pituitary adenoma(NFPA)in 31.4% and prolactinoma in 26.9%. About 64.8% of pituitary adenoma was macroadenoma. Macroadenoma was seen in 73.4 % of growth hormone secreting adenoma, 61.2% in NFPA and 62.0% of prolactinoma (of them six were giant prolactinoma) Conclusion: Pituitary adenoma constituted the bulk of pituitary disorders in Basrah, growth hormone secreting adenoma is the commonest adenoma followed by NFPA and prolactinoma due to referral bias. A change in practice of pituitary adenoma treatment is needed.
Details
- ISSN :
- 20461402
- Volume :
- 7
- Database :
- F1000Research
- Journal :
- F1000Research
- Notes :
- Revised Amendments from Version 1 The research title has been changed based on referee suggestions Inclusion criteria has been made more clear We have corrected typos We clarify that the total number can’t be 232 because some may have more than one diagnosis Miscellaneous cases has been clarified Number in table 3 made more clear Conclusion has been clarified, , [version 2; referees: 2 approved]
- Publication Type :
- Academic Journal
- Accession number :
- edsfor.10.12688.f1000research.13632.2
- Document Type :
- research-article
- Full Text :
- https://doi.org/10.12688/f1000research.13632.2