Advances in Health and Disease. Volume 44

This edited volume includes some of the latest research pertaining to the topics of health and disease. Chapter One examines the interplay between molecular redox signaling and the ubiquitin-proteasome system. Chapter Two discusses the origin and mechanism of antibody development, autoantibodies'association with disease, and the available therapeutic interventions. Chapter Three describes the microbial diversity of breast milk and the factors influencing this diversity. Chapter Four collects the evidence on adolescent bone growth, nutrition, physical activity, and hormonal changes related to occurrence of osteoporosis later in life. Chapter Five reviews evidence regarding the effects of allopurinol and febuxostat in kidney disease. Lastly, Chapter Six examines the phenomenon of elevated serum uric acid in patients with chronic kidney disease.