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The pilot study of the basic pharmacokinetic properties of pyrrolylcarnosine — the new pyrrolic derivative of dipeptide carnosine

Authors :
D. A. Abaimov
Anastasiya V. Khutorova
A. K. Sariev
O. I. Kulikova
M. A. Belousova
S. L. Stvolinsky
V. A. Migulin
T. N. Fedorova
Source :
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 29-36 (2023)
Publication Year :
2023
Publisher :
LLC “Publisher OKI”, 2023.

Abstract

The experimental study of the pharmacokinetic characteristics of a new pyrrole derivative of carnosine, pyrrolylcarnosine, was carried out. Based on the results of the experiment, the basic pharmacokinetic parameters of the drug are expected. The tissues and organs bioavailability was studied. The tropism of pyrrolylcarnosine to the organs of elimination and the ability of pyrrolylcarnosine to penetrate into the heart muscle tissue were shown.

Details

Language :
Russian
ISSN :
25877836 and 26868830
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Фармакокинетика и Фармакодинамика
Publication Type :
Academic Journal
Accession number :
edsdoj.fff5ded2111f457e9ed434b44a96207e
Document Type :
article
Full Text :
https://doi.org/10.37489/2587-7836-2023-2-29-36