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Abdominal and Peripheral Tissue Oxygen Supply during Selective Lower Body Perfusion for the Surgical Repair of Congenital Heart Disease: A Pilot Study

Authors :
Harry Magunia
Jana Nester
Rodrigo Sandoval Boburg
Christian Schlensak
Peter Rosenberger
Michael Hofbeck
Marius Keller
Felix Neunhoeffer
Source :
Journal of Cardiovascular Development and Disease, Vol 9, Iss 12, p 436 (2022)
Publication Year :
2022
Publisher :
MDPI AG, 2022.

Abstract

Background: Lower body perfusion (LBP) may be a strategy for maintaining organ perfusion during congenital heart disease surgery. It is hypothesized that renal and lower limb oxygen supply during LBP is superior to off-pump surgery and comparable to that of a standard cardiopulmonary bypass (CPB). Methods: in this prospective single-center study, patients aged 2), hemoglobin amount (Hb), blood velocity (Velo), and blood flow (Flow) were measured noninvasively. Results: A total of 23 patients were included (group 1, n = 9; group 2, n = 5; group 3, n = 9). Compared to the baseline values, rSO2 and pSO2 decreased significantly in group 2 compared to groups 1 and 3. Conversely, rHB significantly increased in group 2 compared to groups 1 and 3, reflecting abdominal venous stasis. Compared to group 3, group 1 showed a significantly lower pFlow during CPB; however, rFlow, pFlow, and pVelo did not differ. Conclusion: according to these observations, LBP results in an improved renal oxygen supply compared to off-pump surgery and may prove to be a promising alternative to conventional CPB.

Details

Language :
English
ISSN :
23083425
Volume :
9
Issue :
12
Database :
Directory of Open Access Journals
Journal :
Journal of Cardiovascular Development and Disease
Publication Type :
Academic Journal
Accession number :
edsdoj.feced5a85034425c90c1fd1c7eb8701d
Document Type :
article
Full Text :
https://doi.org/10.3390/jcdd9120436