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Effects of Methamphetamine on Single Unit Activity in Rat Medial Prefrontal Cortex In Vivo
- Source :
- Neural Plasticity, Vol 2007 (2007)
- Publication Year :
- 2007
- Publisher :
- Hindawi Limited, 2007.
-
Abstract
- To investigate how neuronal activity in the prefrontal cortex changes in an animal model of schizophrenia, we recorded single unit activity in the medial prefrontal cortex of urethane-anesthetized and awake rats following methamphetamine (MA) administration. Systemic MA injection (4 mg/kg, IP) induced inconsistent changes, that is, both enhancement and reduction, in unit discharge rate, with a subset of neurons transiently (
- Subjects :
- Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Subjects
Details
- Language :
- English
- ISSN :
- 20905904 and 16875443
- Volume :
- 2007
- Database :
- Directory of Open Access Journals
- Journal :
- Neural Plasticity
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.fea4c869750045fbb60bd6d7c6e5ce10
- Document Type :
- article
- Full Text :
- https://doi.org/10.1155/2007/29821