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Predominant Myofibrillar Pathology with Preserved Sarcolemmal Aquaporin 4 Immunoreactivity in a Patient with Neuromyelitis Optica-Associated HyperCKemia
- Source :
- Kosin Medical Journal, Vol 36, Iss 2, Pp 206-210 (2021)
- Publication Year :
- 2021
- Publisher :
- Kosin University College of Medicine, 2021.
-
Abstract
- A 49-year-old man developed recurrent myalgia and hyperCKemia during acute attacks of neuromyelitis optica. Muscle biopsy was performed, and the pathological findings were analyzed. Predominant myofibrillar pathology was observed, which constitutes a unique finding that has not been reported before. This case result shows that neuromyelitis optica-associated hyperCKemia can produce variable pathologic phenotypes. Further studies are needed to elucidate the relationship between myofibril destruction and aquaporin 4 autoimmunity.
Details
- Language :
- English
- ISSN :
- 20059531 and 25867024
- Volume :
- 36
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Kosin Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.fd9b52e06a294b3a8ad5bf1d8b7a5605
- Document Type :
- article
- Full Text :
- https://doi.org/10.7180/kmj.2021.36.2.206