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Landscape of somatic alterations in large-scale solid tumors from an Asian population

Authors :
Liqun Wu
Herui Yao
Hui Chen
Aodi Wang
Kun Guo
Wenli Gou
Yanfei Yu
Xiang Li
Ming Yao
Shaohua Yuan
Fei Pang
Jinwei Hu
Lijuan Chen
Wenjin Liu
Jicheng Yao
Shuirong Zhang
Xiaowei Dong
Weifeng Wang
Jing Hu
Qi Ling
Songming Ding
Yan Wei
Qiang Li
Weichun Cao
Shuang Wang
Yang Di
Feiling Feng
Gang Zhao
Jian Zhang
Ling Huang
Jia Xu
Wangjun Yan
Zhongsheng Tong
Da Jiang
Tao Ji
Qiao Li
Ling Xu
Huiying He
Liang Shang
Jin Liu
Kefeng Wang
Duoguang Wu
Jingnan Shen
Ye Liu
Ting Zhang
Chaojie Liang
Yusheng Wang
Yanhong Shang
Jianji Guo
Guanbiao Liang
Shifeng Xu
Junfeng Liu
Kai Wang
Minghui Wang
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Understanding the mutation landscape of cancer may enable the development of more targeted therapies. Here, the authors sequence a panel of genes in a large Asian cohort and compare to American cohorts and find 64% of the Asian patients have actionable mutations.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.fbff375291249d78d4672701b1ff890
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-31780-9