Back to Search
Start Over
Mimicking Mytilus edulis foot protein: A versatile strategy for robust biomedical coatings
- Source :
- The Innovation, Vol 5, Iss 5, Pp 100671- (2024)
- Publication Year :
- 2024
- Publisher :
- Elsevier, 2024.
-
Abstract
- Summary: Universal coatings with versatile surface adhesion, good mechanochemical robustness, and the capacity for secondary modification are of great scientific interest. However, incorporating these advantages into a system is still a great challenge. Here, we report a series of catechol-decorated polyallylamines (CPAs), denoted as pseudo-Mytilus edulis foot protein 5 (pseudo-Mefp-5), that mimic not only the catechol and amine groups but also the backbone of Mefp-5. CPAs can fabricate highly adhesive, robust, multifunctional polyCPA (PCPA) coatings based on synergetic catechol-polyamine chemistry as universal building blocks. Due to the interpenetrating entangled network architectures, these coatings exhibit high chemical robustness against harsh conditions (HCl, pH 1; NaOH, pH 14; H2O2, 30%), good mechanical robustness, and wear resistance. In addition, PCPA coatings provide abundant grafting sites, enabling the fabrication of various functional surfaces through secondary modification. Furthermore, the versatility, multifaceted robustness, and scalability of PCPA coatings indicate their great potential for surface engineering, especially for withstanding harsh conditions in multipurpose biomedical applications.
- Subjects :
- Science (General)
Q1-390
Subjects
Details
- Language :
- English
- ISSN :
- 26666758
- Volume :
- 5
- Issue :
- 5
- Database :
- Directory of Open Access Journals
- Journal :
- The Innovation
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.fa36936a2571423c9286734f34adbbda
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.xinn.2024.100671