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Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals
- Source :
- Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
- Publication Year :
- 2023
- Publisher :
- Nature Portfolio, 2023.
-
Abstract
- The role of empty lipid nanoparticles in eliciting dendritic cell maturation and innate immune signaling is shown to be impaired in older adults, potentially contributing to lower immune responses to SARS-CoV-2 mRNA-based vaccines.
- Subjects :
- Biology (General)
QH301-705.5
Subjects
Details
- Language :
- English
- ISSN :
- 23993642
- Volume :
- 6
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Communications Biology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f939a91eb95f4c4fb669b5245aa1ee19
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s42003-023-04555-1