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Prophages and satellite prophages are widespread in Streptococcus and may play a role in pneumococcal pathogenesis

Authors :
Reza Rezaei Javan
Elisa Ramos-Sevillano
Asma Akter
Jeremy Brown
Angela B. Brueggemann
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Prophages are viral genomes integrated within bacterial genomes. Here, Rezaei Javan et al. identify nearly 800 prophages and satellite prophages in > 1300 Streptococcus genomes, and show that a satellite prophage is associated with virulence in a mouse model of pneumococcal infection.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f8ad0d9a144a429081aa2df04cd9add5
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-12825-y