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Too young for an acquired cardiomyopathy? Cobalt metallosis as a cardiac amyloidosis mimicker

Authors :
Mihnea Casian
Ramona Bica
Virgil Ionescu
Vlad Predescu
Radu Țincu
Ruxandra Jurcuț
Source :
ESC Heart Failure, Vol 11, Iss 2, Pp 1236-1241 (2024)
Publication Year :
2024
Publisher :
Wiley, 2024.

Abstract

Abstract Metallosis with subsequent cardiac involvement is a possible long‐term complication of hip arthroplasty. We report the case of a young female referred to our centre for the suspicion of cardiac amyloidosis presenting with low electrocardiogram voltage, left ventricular hypertrophy, pericardial effusion, and global and longitudinal systolic impairment with apical sparing pattern. Her medical history was remarkable for arthroplasty in the context of congenital hip dysplasia. Two years prior to presentation, she underwent revision surgery for prosthesis malfunction, and tissue metallosis was initially documented. At the current presentation, cobalt metallosis was confirmed, as the circulating cobalt and chromium levels were severely elevated. The accurate diagnosis prompted the removal of the cobalt source with extensive tissue debridement and the use of chelating agents. Reversal of the cardiac abnormalities occurred as the circulating cobalt levels returned to normal.

Details

Language :
English
ISSN :
20555822
Volume :
11
Issue :
2
Database :
Directory of Open Access Journals
Journal :
ESC Heart Failure
Publication Type :
Academic Journal
Accession number :
edsdoj.f8984794d484f9aac330b3e878d4405
Document Type :
article
Full Text :
https://doi.org/10.1002/ehf2.14695