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Control of protein stability by post-translational modifications

Authors :
Ji Min Lee
Henrik M. Hammarén
Mikhail M. Savitski
Sung Hee Baek
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

Here the authors summarize current knowledge of the regulation of protein stability by various post-translational modifications (PTMs) including methylation and phosphorylation. PTM-regulated degrons act as signals for protein degradation or stabilization.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f88c9d079d464be59ac498ecc3cbd655
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-023-35795-8
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