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ATP-dependent modulation of MgtE in Mg2+ homeostasis

Authors :
Atsuhiro Tomita
Mingfeng Zhang
Fei Jin
Wenhui Zhuang
Hironori Takeda
Tatsuro Maruyama
Masanori Osawa
Ken-ichi Hashimoto
Hisashi Kawasaki
Koichi Ito
Naoshi Dohmae
Ryuichiro Ishitani
Ichio Shimada
Zhiqiang Yan
Motoyuki Hattori
Osamu Nureki
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

Author summary MgtE is an Mg2+ transporter involved in Mg2+ homeostasis. Here, the authors report that ATP regulates the Mg+2-dependent gating of MgtE and use X-ray crystallography combined with functional studies to propose the molecular mechanisms involved in this process.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f888e0a3dea7456dbdf43ae0cd85611d
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-00082-w