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Engineering of a fluorescent chemogenetic reporter with tunable color for advanced live-cell imaging

Authors :
Hela Benaissa
Karim Ounoughi
Isabelle Aujard
Evelyne Fischer
Rosette Goïame
Julie Nguyen
Alison G. Tebo
Chenge Li
Thomas Le Saux
Giulia Bertolin
Marc Tramier
Lydia Danglot
Nicolas Pietrancosta
Xavier Morin
Ludovic Jullien
Arnaud Gautier
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Fluorescent reporters spanning the visible spectrum are needed for imaging live cells and organisms. Here the authors report a collection of fluorogenic chromophores that cover the visible spectrum from blue to red using a single engineered and optimised protein tag.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f8876daa7ff41be9c6ff80c673882dd
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-27334-0