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Association between COVID-19 and Male Fertility: Systematic Review and Meta-Analysis of Observational Studies
- Source :
- The World Journal of Men's Health, Vol 41, Iss 2, Pp 311-329 (2023)
- Publication Year :
- 2023
- Publisher :
- Korean Society for Sexual Medicine and Andrology, 2023.
-
Abstract
- Purpose: Whether COVID-19 reduces male fertility remains requires further investigation. This meta-analysis and systematic review evaluated the impact of COVID-19 on male fertility. Materials and Methods: The literature in PubMed, Embase, MEDLINE, Web of Science, and Cochrane Library up to January 01, 2022 was systematically searched, and a meta-analysis was conducted to investigate the effect of COVID-19 on male fertility. Totally 17 studies with a total of 1,627 patients and 1,535 control subjects were included in our meta-analysis. Results: Regarding sperm quality, COVID-19 decreased the total sperm count (p=0.012), sperm concentration (p=0.001), total motility (p=0.001), progressive sperm motility (p=0.048), and viability (p=0.031). Subgroup analyses showed that different control group populations did not change the results. It was found that during the illness stage of COVID-19, semen volume decreased, and during the recovery stage of COVID-19, sperm concentration and total motility decreased
Details
- Language :
- English
- ISSN :
- 22874208 and 22874690
- Volume :
- 41
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- The World Journal of Men's Health
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f87d4f134f46769ebf9b682f711525
- Document Type :
- article
- Full Text :
- https://doi.org/10.5534/wjmh.220091