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Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection

Authors :
Benjamin M. Tang
Maryam Shojaei
Sally Teoh
Adrienne Meyers
John Ho
T. Blake Ball
Yoav Keynan
Amarnath Pisipati
Aseem Kumar
Damon P. Eisen
Kevin Lai
Mark Gillett
Rahul Santram
Robert Geffers
Jens Schreiber
Khyobeni Mozhui
Stephen Huang
Grant P. Parnell
Marek Nalos
Monika Holubova
Tracy Chew
David Booth
Anand Kumar
Anthony McLean
Klaus Schughart
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Identification of host factors associated with severe influenza infection could provide insights into treatment options. Here, the authors provide transcriptomic analyses of blood from >100 influenza infected patients and show that changes in circulating neutrophils are associated with severe influenza infection.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f8717f61b4914b2fa628be04cd6755a4
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-11249-y