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Peroral endoscopic full and partial-thickness myotomy. A viability study in an animal model

Authors :
C.D. Quiroz-Guadarrama
M. Rojano-Rodríguez
J.J. Herrera-Esquivel
F. de la Concha-Bermejillo
L.S. Romero-Loera
I. Estrada-Moscoso
I. del Rio-Suarez
J.M. Morales-Vargas
M.F. Torres-Ruiz
J.A. Gonzalez-Angulo
J.L. Beristain-Hernandez
J. Alonso-Lárraga
E. Cárdenas-Lailson
M. Moreno-Portillo
Source :
Revista de Gastroenterología de México (English Edition), Vol 78, Iss 4, Pp 225-230 (2013)
Publication Year :
2013
Publisher :
Elsevier, 2013.

Abstract

Background: Peroral endoscopic myotomy has recently been developed and performed on patients with good results. Aims: To evaluate the technical feasibility of peroral endoscopic full-thickness and partial thickness myotomy in a porcine model. Material and methods: Eighteen criollo pigs were randomly assigned to 2 groups: group A (partial-thickness myotomy) and group B (full-thickness myotomy). The mucosal defect proximal to the myotomy site was left open. On the seventh postoperative day the pig was euthanized and follow-up surgical exploration was performed. The duration of each procedure, postoperative progression of the animal, complications, and anatomopathologic findings were registered. Results: The procedure was viable in all the pigs. The mean surgery duration was 81 ± 35.3 min (group A 51.11 ± 11.12, group B 111 ± 22.61; P

Details

Language :
English
ISSN :
2255534X and 23832614
Volume :
78
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Revista de Gastroenterología de México (English Edition)
Publication Type :
Academic Journal
Accession number :
edsdoj.f798c238326141f7abb811fd0330c659
Document Type :
article
Full Text :
https://doi.org/10.1016/j.rgmxen.2014.02.005